Granulocyte Transfusion in Febrile Neutropenia
نویسندگان
چکیده
منابع مشابه
Clinical practice in febrile neutropenia risk assessment and granulocyte colony-stimulating factor primary prophylaxis of febrile neutropenia in Poland
AIM OF THE STUDY The first aim was to investigate the knowledge and awareness of oncologists concerning febrile neutropenia (FN) risk assessment and indications for granulocyte colony-stimulating factor (G-CSF) primary prophylaxis (PP), based on current therapeutic guidelines (PTOK and EORTC). The second aim was to educate the oncologists on best practices for risk assessment and neutropenia ma...
متن کاملManagement of Febrile Neutropenia
Bacterial Pathogens Bacteria are the predominant organisms. In the late 1950’s/early 1960’s Gram+ve organisms were the commonest, particularly Staphylococcus aureus. The late 1960’s/early 1970’s were typified by Gram-ve of gastrointestinal tract origin, particularly Escherischia coli, Klebsiella spp and Pseudomonas spp. By the 1990’s Staphylococcus spp including coagulase negative organisms, St...
متن کاملFebrile neutropenia in haematological malignancies.
Fever is the principle sign of infection in neutropenic patient and frequently may be the only evidence of infection. The pattern of fever in neutropenia is non-specific and not pathognomonic of any type of infections or non-infectious process and can be suppressed by the antipyretic effects of drugs such as corticosteroids. Neutropenia, resulting from cytotoxic chemotherapy is the most common ...
متن کاملGranulocyte colony-stimulating factor in the treatment of high-risk febrile neutropenia: a multicenter randomized trial.
BACKGROUND Granulocyte colony-stimulating factors (G-CSFs) have been shown to help prevent febrile neutropenia in certain subgroups of cancer patients undergoing chemotherapy, but their role in treating febrile neutropenia is controversial. The purpose of our study was to evaluate-in a prospective multicenter randomized clinical trial-the efficacy of adding G-CSF to broad-spectrum antibiotic tr...
متن کاملDose-Dependent Effect of Granulocyte Transfusions in Hematological Patients with Febrile Neutropenia
It is still under debate whether granulocyte transfusions (GTs) substantially increase survival in patients with febrile neutropenia. We retrospectively examined data relative to 96 patients with hematological malignancies receiving 491 GTs during 114 infectious episodes (IE). Patients were grouped according to the median doses of granulocytes transfused during the infectious episode (low-dose ...
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ژورنال
عنوان ژورنال: Blood
سال: 2015
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v126.23.4612.4612